Content
⇒ Eukaryotic Viruses
⇒ Viral Structure
⇒ Animal Viruses
⇒ Oncogenic Viruses
⇒ Plant Viruses
All viruses are noncellular infectious agents that proliferate
only within cells. Although eukaryotic cells
and their viruses carry out many of the same processes
of bacteriophages, the details of these
processes differ, especially those carried out in specialized
organelles. Some important processes are
found almost exclusively in eukaryotes and their
viruses; among these are RNA processing (exon
splicing) and protein modifications (proteolytic cleavage, glycosylation,
and phosphorylation). |
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Viruses that infect eukaryotic cells consist of a nucleic acid, either
DNA or RNA, covered by a protein coat, a capsid. A single protein subunit
of the capsid is referred to as a capsomere. The capsids of most eukaryotic
viruses consist of a number of different proteins. The complex
of nucleic acid and capsid is designated the nucleocapsid. Many animal
viruses are surrounded by a membrane (lipid bilayer) derived from the
host cell in which they proliferate. These viruses are said to be enveloped.
The complete, intact virus particle is referred to as a virion.
The primary characteristics used to differentiate eukaryotic viruses
are associated with their nucleic acid. First, viruses may be separated
based on whether they are DNA viruses or RNA viruses. The nucleic
acid may be single-stranded (ss) or double-stranded (ds), depending on
the species. If the ssRNA is able to function as mRNA it is referred to as
plus strand RNA (+RNA); if it is the equivalent to antisense RNA it is
known as minus strand RNA (-RNA). Some of the genomes in plant
and animal viruses are fragmented into segments. Virion shape is also
used to differentiate among the viruses since they have a number of
distinctive forms: cylindrical or helical, spherical, icosahedral, bulletshaped,
or even more complex shapes. The presence or absence of an envelope
and the virion size are also helpful in distinguishing viruses.
Notes
Viruses are not considered “living” organisms.
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