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Section: Genetics » Regulation of Gene Expression » Mechanisms in Eukaryotes
 
 
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  Masked mRNA in eggs of sea urchin and Xenopus
 
     
 
Content
⇒ Regulation of Gene Expression 3. A Variety of Mechanisms in Eukaryotes
⇒ Regulation at Transcription Level
⇒ Activation of transcription
⇒ Britten-Davidson model for unit of transcription
⇒ Gene battery
⇒ Chromosomal proteins and gene expression
⇒ Repression of transcription 
⇒ Specific DNA sequences controlling transcription
⇒ Transgenic plants to study regulatory sequences
⇒ Modification of DNA sequences and their transcripts in gene expression
⇒ Alternative splicing of transcripts
⇒ Regulation at translation level
⇒ Activation and repression of translation
⇒ Masked mRNA in eggs of sea urchin and Xenopus
⇒ Regulation by gene re-arrangement
⇒ Expression of immunoglobulin genes
⇒ Yeast mating type switching
⇒ Trypanosome surface antigen (VSG) switching
⇒ Synthesis of mRNA in pieces in VSG genes in trypanosome
⇒ Regulation by reversible phosphorylation
⇒ Signal transduction and second messengers
⇒ Proteins and peptide hormones and gene expression
⇒ Steroid hormones and gene expression
⇒ Interferon stimulated gene expression (without a second messenger)
⇒ Cell surface receptors in cholesterol metabolism and drug production
⇒ Ubiquitin protein and regulation of heat shock genes
Masked mRNA in eggs of sea urchin and Xenopus
There are also several examples of 'masked mRNA' in eggs and oocytes, which may indicate translational control. This 'masked mRNA' is found in abundant quantity and remains untranslated until after fertilization. There are atleast two examples of this masked mRNA' : (i) the mRNA coding for small subunit of ribonucleotide reductase in clam and sea urcin eggs and (ii) the mRNA for fibronectin in Xenopus unfertilized eggs, remain untranslated until about 6-7 hours after fertilization (midblastula stage). The mechanism of this unmasking is not clearly understood.

 
     






     
     
 
 
     
 
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