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Section: Genetics » Organization of Genetic Material » Split, Overlapping & Pseudogenes
 
 
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  Exon sequences are conserved, but intron sequences vary
 
     
 
Content
⇒ Organization of Genetic Material 3.  Split Genes, Overlapping Genes and Pseudogenes
⇒ Split genes or interrupted genes 
⇒ Discovery and nature of split genes
⇒ R-loop mapping and restriction mapping of interrupted genes
⇒ Structure of chicken ovalbumin split gene
⇒ Split genes in fungal mitochondria
⇒ Split genes in chloroplasts
⇒ Intron of one gene may contain exon of another gene
⇒ Exon sequences are conserved, but intron sequences vary
⇒ Introns with coding sequences
⇒ Overlapping genes
⇒ Pseudogenes
⇒ Promiscuous DNA
Exon sequences are conserved, but intron sequences vary
Through the use of recombination DNA technology, it could be shown that the exon sequences of more than one genes (for same related functions) in the same species or in different species, often have similar DNA sequences. However, the corresponding intron sequences differ substantially. This was demonstrated for two β globin genes of mouse. This property has been utilized in selecting exon sequences of heterologous genes for isolation of related genes in different species.

 
     






     
     
 
 
     
 
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